Since the driving distance from California to Orange Beach is a whopping 33 hours (2 hours less than PCB or Destin), you will need some interesting stops to keep things fun. The fastest route to take is I-40 and the actual distance in miles is 2200. There are many nice places to stop and take a break on your way like Albuquerque, New Mexico and Dallas, Texas. You’ll also be going through a part of the Tonto National Forest in Arizona at Flagstaff, the El Malpais National Conservation area before Albuquerque and also De Soto National Forest right before you get to Orange Beach, AL.
If you take route I-10 instead, you will be passing through Phoenix and Tucson, Arizona, El Paso in New Mexico, San Antonio and Houston in Texas and Louisiana, New Orleans.